Why We Get Sick: The Hidden Epidemic at the Root of Most Chronic Disease―and How to Fight It

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Why We Get Sick: The Hidden Epidemic at the Root of Most Chronic Disease―and How to Fight It

Why We Get Sick: The Hidden Epidemic at the Root of Most Chronic Disease―and How to Fight It

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Randy: You know, it's so surprising that medicine hasn't used all of evolutionary biology for a long, long time. It's been 130 years since Darwin when published his wonderful book On the Origin of Species, and even now, most doctors never have a chance to learn the basics of evolutionary biology. They might a little bit, but not the more interesting things for medicine. Like, for instance, how natural selection shaped fever and why it hurts when you skin your knee. These are profoundly important things for doctors to learn. And these are the kinds of questions that we ask in evolutionary medicine. It's not a special kind of practice, it's just using the basics of evolution the same way we use genetics, and physiology, and other kinds of things. A scientist reveals the groundbreaking evidence linking many major diseases, including cancer, diabetes, and Alzheimer’s disease, to a common root cause—insulin resistance—and shares an easy, effective plan to reverse and prevent it. If you’re doing aerobic, try interval training. If you’re doing resistance, do sets to failure. This makes aerobic and resistance training more similar to each other. During winter, levels of UV radiation are much lower than in summer. This has a direct effect on how much vitamin D our bodies can make.

Why Do We Get Sick? - Ask A Biologist

He mentioned various inflammatory conditions including autoimmune, infectious, etc, which are associated with IR. Facing this escalating "arms races," we have learned that we need to avoid long-term antibiotic use to prevent antibiotic-resistant pathogens from upgrading. Refeeding syndrome results from a spike in insulin (and movement of certain electrolytes, etc.), so breaking a long fast with processed carbs is a bad idea. Kidneys: IR makes kidney stones more likely by stimulating PTH to raise calcium, and also making the urine more alkaline. Randy: It's pretty simple, really. Ask questions that you find interesting and try to figure out ways to answer them. I see a lot of kids actually who think they want to become a scientist and therefore start taking really hard courses and trying to get into the best college and all that kind of stuff. And some of them get burned out because a lot of the stuff that they try to teach you in school, it's pretty boring. Um, but if you have your own questions and you're just playing curious about things and you pursue them, no matter what the teacher says, then you're going to have a good time and nobody can stop you.

Both aerobic and resistance training are effective, but if you can only do a little bit of exercise, resistance is probably better.

Why We Get Sick - Podcast Episode 98 | Ask A Biologist Why We Get Sick - Podcast Episode 98 | Ask A Biologist

The only disease for which it seems reasonable to define insulin resistance as the “root cause” is type 2 diabetes, as it is a fundamental component of its pathology. Insulin resistance associates with many other diseases and in some cases there is evidence that it contributes to causing those diseases, but implying there is a unified single root cause for most diseases without strong evidence is unjustified. Randy: There are times when people just feel sad and this doesn't feel good at all and people wonder are things ever going to get better again in life? And some people blame themselves for that feeling and say, I should just quit it. But you know what? After we lose something, whether it's someone we care about or even a toy, or sometimes when we fail on an examination, we just plain and feel sad. It turns out that even though that feels bad, it's a kind of normal and useful feeling. Now it goes overboard a lot. Just like that smoke detector does, a lot of times it's too much, too long. But that feeling, it's really normal when you lose something It helps us to not lose it again and to try to replace it and to, you know, try to pause in life a little bit and see what else we might do differently. Avoid the temptation to restrict protein, even on a ketogenic diet. 1 – 1.5 g per kg body weight is decent, but you probably need more as you get older. Novel environments . Environments our evolved bodies aren't used to handling. A mismatch between our design and our environment.

Magnesium seems to help. Chromium does as well, a study showed significant improvement while supplementing that went away after supplementing. Although most cases of the common cold and flu tend to go away by themselves, every year, flu kills an estimated 290,000 to 650,000 people worldwide. It will be necessary to treat any disease affecting the immune system, and this will usually involve different types of medication. Other temperate locations across the globe see similar patterns, with cold temperatures and low humidity being the prime factors, according to one 2013 analysis. The same cannot be said for tropical areas, however. There was an understanding of hormones’ influence on obesity in early 1900s, but starting in mid 1900s the “calories in calories out” dogma started catching on. This approach is oversimplified and ignores the roles of hormones in weight gain, insulin chief among them.

Why We Get Sick: The New Science of Darwinian [PDF] [EPUB] Why We Get Sick: The New Science of Darwinian

Keep in mind muscle weighs more than fat, so you won’t be losing as much weight when you do resistance training. Randy: There sure is. And just like we talked about with pain, you know, if you don't have pain, you're in even worse trouble than a person who has pain. But what about people who don't have anxiety? There are people like that and they don't come to doctors saying, Dr, please, I don't have enough anxiety and nervousness, can you please help me? But they sure do get in trouble. I mean, they do wild and dangerous and crazy things. You know, just in the last couple of weeks for people have fallen into the Grand Canyon and died. If they had been more nervous and wary, they would still be alive today.


Consequently, some people believe that taking vitamin D supplements during the winter months can help keep flu at bay. Indeed, a 2010 clinical trial showed that school children who took vitamin D3 daily had a lower risk of contracting influenza A.

Why do they strike in winter? - Medical News Today Colds and flu: Why do they strike in winter? - Medical News Today

Related: TG/HDL < 2.0 is a good sign for LDL particle size. Statins increase the ratio of small / big LDL, which is bad.)Reproductive success at a cost to health. Natural selection doesn’t work to directly increase lifelong health. Instead, it only acts on traits that affect our reproductive success. While many traits that increase reproductive success are linked to positive health (you have to live to reproduce, after all), some traits that increase reproductive success can be bad for overall health. For example, high production of the hormone testosterone helps males have more offspring, but it also increases the chances for testicular cancer and heart disease. This increased risk of disease is worth the benefit to reproductive success. Diseases that affect reproduction are heavily selected against. Diseases that don’t affect reproduction—especially diseases that generally occur after reproductive years—don’t face the same strength of selection. Dr. Biology: Right. In this case, doing it. You say run towards it, going towards it. Yes. So in this case, give a talk give more than one or two talks... depending on your answers to IR survey, rough suggestion: 2+, 5% carbs, 1+, 10% carbs, 0+ 20% carbs (about 50 , 75, or 100 grams of carbs per day. 25% protein for each). Be careful with meal replacement shakes – they often have a lot of sugar, refined carbs, and/or seed oils. Better options exist but not necessarily at your grocery store. These rules also apply to influenza. However, receiving a yearly flu shot is the best way of preventing flu.

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